Samuel (calf) has been ruled out for Sunday's game against the Rams, Matt Barrows of The Athletic reports.
Kittle (hamstring) is listed as doubtful for Sunday's game against the Rams, Matt Barrows of The Athletic reports.
Kittle (hamstring) isn't practicing Friday, Eric Branch of the San Francisco Chronicle reports.
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Hufanga (knee) will be on a snap count Sunday against the Rams, David Lombardi of The San Francisco Standard reports.
Pearsall (chest) ran routes on a side field Thursday, Matt Barrows of The Athletic reports.
49ers GM John Lynch said Friday that Cowing "may get some [opportunities]" in Sunday's game against the Rams, Matt Barrows of The Athletic reports.