Kittle (hamstring) isn't practicing Friday, Eric Branch of the San Francisco Chronicle reports.

🔥 Hot Takes

It's a poor sign for his Week 3 availability after Kittle was a mid-week addition to the injury report, initially listed as a non-participant Thursday. Another absence suggests this is more than just caution over minor soreness/tightness, likely setting Kittle up for a game designation on the final injury report ahead of Sunday's matchup with the Rams.

SleeperBot • 3 hours ago

Samuel (calf) has been ruled out for Sunday's game against the Rams, Matt Barrows of The Athletic reports.

SleeperBot • 3 hours ago

Kittle (hamstring) is listed as doubtful for Sunday's game against the Rams, Matt Barrows of The Athletic reports.

SleeperBot • 7 hours ago

49ers may target Haason Reddick to pair with Nick Bosa for stronger pass rush before Brock Purdy's extension

SleeperBot • 8 hours ago

Fred Warner earns NFL's top defensive grade, praised by John Lynch and Nick Bosa

SleeperBot • 9 hours ago

Hufanga (knee) will be on a snap count Sunday against the Rams, David Lombardi of The San Francisco Standard reports.

SleeperBot • 9 hours ago

Pearsall (chest) ran routes on a side field Thursday, Matt Barrows of The Athletic reports.

SleeperBot • 9 hours ago

49ers GM John Lynch said Friday that Cowing "may get some [opportunities]" in Sunday's game against the Rams, Matt Barrows of The Athletic reports.

SleeperBot • 1 day ago

Ward (hamstring) did not participate in Thursday's practice session, Matt Maiocco of NBC Sports Bay Area reports.