Alec Pierce shines as deep threat with Anthony Richardson, while Jonathan Taylor's strong run game continues; Michael Pittman Jr. struggles

Alec Pierce has recently emerged as a deep threat, especially with a notable performance of 81 yards and a touchdown in his last game, and Anthony Richardson's preference for deep throws could enhance Pierce's production. Jonathan Taylor remains a consistent running threat, having surpassed the 100-yard rushing mark three times this season, and the Colts may rely on the run game as Richardson returns to action. Michael Pittman Jr. has experienced a decline in performance, recording only 16 and 14 yards in his last two games despite his talents.