49ers RB Christian McCaffrey is targeting an early November return as he rehabs from Achilles tendinitis, per @RapSheet

49ers TE George Kittle has been ruled out.

Rams WR Puka Nacua is headed to the medical tent after scoring a TD.

Raheem Mostert has a hip injury and is questionable to return.

Chiefs RB Isiah Pacheco (ankle) is expected to be healthy for Week 12 game vs. Panthers, per @RapSheet It’ll be a coaches decision whether he plays as Kansas City will be on a short week.

49ers TE George Kittle (hamstring) is unlikely to play vs. the Seahawks, per @AdamSchefter

Cowboys WR CeeDee Lamb is a late add to the injury report (back), per @AdamSchefter He is questionable for MNF.

49ers TE George Kittle (hamstring) is questionable for Sunday’s game against Seattle, per @AdamSchefter

The Jaguars have ruled out QB Trevor Lawrence and RB Tank Bigsby for Sunday's game at Detroit, per @TomPelissero