WR Brandon Aiyuk has been taking contract negotiations "personal" and is unhappy with the current offers from San Francisco. Aiyuk is the one who requested a meeting today - and is comfortable playing elsewhere if the 49ers are willing to trade him. (via @Realrclark25)

The Cardinals are placing Bam Knight on IR, ending his season.

Packers RB Marshawn Lloyd suffered another hamstring injury and is likely done for regular season, per @AdamSchefter

Mike McDaniel on if he's considering a QB change: "The QB play last night was not good enough. So everything is on the table." (@Schultz_Report)

Darren Waller (MIA-TE) now has 24.0 fantasy points in PPR (18.0 standard), outperforming his projection by 16.5 points with 2:31 remaining in the 4 quarter

WR Rome Odunze (foot) is considered week-to-week right now, per @JFowlerESPN

Davante Adams is week-to-week with a hamstring injury, per @RapSheet The Rams play Seattle on TNF.

Steelers RB Jaylen Warren (illness) is active for MNF.

WR Ricky Pearsall aggravated his PCL injury and is also dealing with a low ankle sprain, per @nwagoner 49ers HC Kyle Shanahan acknowledged "there is a concern" and is unsure if Pearsall will practice this week.